Assassination Classroom is a Japanese science fiction comedy manga series written and illustrated by Yusei Matsui. The series follows the daily life of an extremely powerful octopus-like being working as a junior high homeroom teacher, and his students dedicated to the task of assassinating him to prevent Earth from being destroyed. The students are considered "misfits" in their school and are taught in a separate building; the class he teaches is called 3-E. It was serialized in Shueisha's shōnen manga magazine Weekly Shōnen Jump from July 2012 to March 2016, with its chapters collected in twenty-one tankōbon volumes.

Assassination Classroom is a 2015 Japanese school science-fiction action comedy film directed by Eiichirō Hasumi and based on the manga series of the same name created by Yūsei Matsui. It was released in Japan on March 21, 2015. A sequel titled Assassination Classroom: Graduation was released in 2016.