The Athlon 64 X2 is the first native dual-core desktop central processing unit (CPU) designed by Advanced Micro Devices (AMD). It was designed from scratch as native dual-core by using an already multi-CPU enabled Athlon 64, joining it with another functional core on one die, and connecting both via a shared dual-channel memory controller/north bridge and additional control logic. The initial versions are based on the E stepping model of the Athlon 64 and, depending on the model, have either 512 or 1024 KB of L2 cache per core. The Athlon 64 X2 can decode instructions for Streaming SIMD Extensions 3 (SSE3), except those few specific to Intel's architecture. The first Athlon 64 X2 CPUs were released in May 2005, in the same month as Intel's first dual-core processor, the Pentium D.

A multi-core processor is a microprocessor on a single integrated circuit with two or more separate processing units, called cores, each of which reads and executes program instructions. The instructions are ordinary CPU instructions but the single processor can run instructions on separate cores at the same time, increasing overall speed for programs that support multithreading or other parallel computing techniques. Manufacturers typically integrate the cores onto a single integrated circuit die or onto multiple dies in a single chip package. The microprocessors currently used in almost all personal computers are multi-core.