Avenida Santa Fe is one of the principal thoroughfares in Buenos Aires, Argentina. The artery is essential to the imaginary axis of Barrio Norte in Buenos Aires, comprising the areas influenced by the route of the avenue through Retiro, Recoleta and Palermo neighborhoods, it is considered one of the main shopping and strolling areas of the city, its many boutiques range from elegant to edgy, which has led it to be dubbed the 'Avenue of Fashion'. Upscale Alto Palermo, at Avenida Coronel Díaz, is one of the city's best-known vertical malls. Avenida Santa Fe is also an attraction for its architecture, strongly reminiscent of Paris. Its name pays homage to the eponymous province in Argentina.

Retiro is a barrio or neighborhood in Buenos Aires, Argentina. Located in the northeast end of the city, Retiro is bordered on the south by the Puerto Madero and San Nicolás, and on the west by the Recoleta.