Axel Gustafsson Oxenstierna was a Swedish statesman and Count of Södermöre. He became a member of the Swedish Privy Council in 1609 and served as Lord High Chancellor of Sweden from 1612 until his death. He was a confidant of King Gustavus Adolphus and then Queen Christina, for whom he was at first regent.

The Lord High Chancellor, literally Chancellor of the Realm, was a prominent and influential office in Sweden, from 1538 until 1799, excluding periods when the office was out of use. The office holder was a member of the Privy Council. From 1634, the Lord High Chancellor was one of five Great Officers of the Realm, who were the most prominent members of the Privy Council and headed a governmental branch each—the Lord High Chancellor headed the Privy Council. In 1792, more than a century after the office's abolition in 1680, it was revived, but was then finally abolished again seven years later in 1799.