The Büyük Menderes River, is a river in southwestern Turkey. It rises in west central Turkey near Dinar before flowing west through the Büyük Menderes graben until reaching the Aegean Sea in the proximity of the ancient Ionian city Miletus. The river was well known for its sinuous, curving pattern, and gives its name to the common term used to describe these characteristic bends in rivers.

Ionia was an ancient region on the western coast of Anatolia, to the south of present-day İzmir, Turkey. It consisted of the northernmost territories of the Ionian League of Greek settlements. Never a unified state, it was named after the Ionians who had settled in the region before the archaic period.