The Mk/B53 was a high-yield bunker buster thermonuclear weapon developed by the United States during the Cold War. Deployed on Strategic Air Command bombers, the B53, with a yield of 9 megatons, was the most powerful weapon in the U.S. nuclear arsenal after the last B41 nuclear bombs were retired in 1976.

A nuclear bunker buster, also known as an earth-penetrating weapon (EPW), is the nuclear equivalent of the conventional bunker buster. The non-nuclear component of the weapon is designed to penetrate soil, rock, or concrete to deliver a nuclear warhead to an underground target. These weapons would be used to destroy hardened, underground military bunkers or other below-ground facilities. An underground explosion releases a larger fraction of its energy into the ground, compared to a surface burst or air burst explosion at or above the surface, and so can destroy an underground target using a lower explosive yield. This in turn could lead to a reduced amount of radioactive fallout. However, it is unlikely that the explosion would be completely contained underground. As a result, significant amounts of rock and soil would be rendered radioactive and lofted as dust or vapor into the atmosphere, generating significant fallout.