The Bacillus Calmette–Guérin vaccine is a vaccine primarily used against tuberculosis. It is named after its inventors Albert Calmette and Camille Guérin. In countries where tuberculosis or leprosy is
Microscopic image of the Calmette–Guérin bacillus, Ziehl–Neelsen stain, magnification: 1,000nn
Micrograph showing granulomatous inflammation of bladder neck tissue due to Bacillus Calmette–Guérin used to treat bladder cancer, H&E stain
An apparatus (4–5 cm length, with 9 short needles) used for BCG vaccination in Japan, shown with ampules of BCG and saline
French poster promoting the BCG vaccine
The smallpox vaccine is used to prevent smallpox infection caused by the variola virus. It is the first vaccine to have been developed against a contagious disease. In 1796, British physician Edward J
BCG vaccine
…The characteristic raised scar that BCG immunization leaves is often used as proof of prior immunization. This scar must be distinguished from that of smallpox vaccination, which it may resemble. When given for bladder cancer, the vaccine is not injected through the skin but is instilled into the bladder (intravesical…
The smallpox vaccine diluent in a syringe alongside a vial of Dryvax dried smallpox vaccine and bifurcated needle
Ovine smallpox vaccine, manufactured by growing live vaccinia in sheep, 1980s
MVA-BN smallpox vaccine vial
Dr Edward Jenner performing his first vaccination on James Phipps, a boy of age 8. 14 May 1796. Painting by Ernest Board (early 20th century).