BC Prienai was a Lithuanian professional basketball club based in Prienai. They played domestically in the Lithuanian Basketball League every year since winning the promotion in 2009. During the 2008–09 season, then called Rūdupis, they became the champion of the NKL and won the challenge match for a slot in the LKL. In their debut LKL season Rūdupis took seventh place, while next two seasons brought BC Prienai two bronze LKL medals. BC Prienai played in EuroCup 2011–12 with moderate success; the team won 3 games out of 6, but nonetheless failed to qualify for the next stage. More recently, the team has become a strong competitor in domestic tournaments, more than once upsetting teams such as Žalgiris Kaunas and Lietuvos rytas Vilnius. In December 2017, in a highly publicized move, Vytautas signed American basketball players and brothers LaMelo and LiAngelo Ball.

Prienai is a city in Lithuania situated on the Nemunas River, 29 km (18 mi) south of Kaunas. In 2023 the city had 8,894 inhabitants. The name of the city is a derivative from a surname Prienas. Pociūnai Airport is associated with the city.