The Banu Munqidh, also referred to as the Munqidhites, were an Arab family that ruled an emirate in the Orontes Valley in northern Syria from the mid-11th century until the family's demise in an earthquake in 1157. The emirate was initially based in Kafartab before the Banu Munqidh took over the fortress of Shayzar in 1081 and made it their headquarters for the remainder of their rule. The capture of Shayzar was the culmination of a long, drawn-out process beginning with the Banu Munqidh's nominal assignment to the land by the Mirdasid emir of Aleppo in 1025, and accelerating with the weakened grip of Byzantine rule in northern Syria in the 1070s.

The Banu Kalb was an Arab tribe which mainly dwelt in the desert and steppe of northwestern Arabia and central Syria. It was involved in the tribal politics of the Byzantine Empire's eastern frontiers, possibly as early as the 4th century. By the 6th century, the Kalb had largely adopted Christianity and came under the authority of the Ghassanids, leaders of the Byzantines' Arab allies. During the lifetime of the Islamic prophet Muhammad, a few of his close companions were Kalbites, most prominently Zayd ibn Haritha and Dihya, but the bulk of the tribe remained Christian at the time of Muhammad's death in 632. They began converting in large numbers when the Muslims made significant progress in the conquest of Byzantine Syria, in which the Kalb stayed neutral. As a massive nomadic tribe with considerable military experience, the Kalb was sought as a key ally by the Muslim state. The leading clans of the Kalb forged marital ties with the Umayyad family, and the tribe became the military foundation of the Syria-based Umayyad Caliphate (661–750) from the reign of Mu'awiya I to the early reign of Abd al-Malik.