La Latina is a historic neighborhood in the Centro district of downtown Madrid, Spain. La Latina occupies the place of the oldest area in Madrid, the Islamic citadel inside the city walls, with narrow streets and large squares. It is administratively locked almost entirely within the district of Palacio in Centro. It was named after the old hospital, founded in 1499 by Beatriz Galindo "La Latina". It occupies a large part of what is known as El Madrid de los Austrias, and although its boundaries are subjective, it could be argued that it was essentially the vicinity of the carrera de San Francisco street - that continues from the Plaza de la Cebada up to the San Francisco el Grande Basilica. These limits are: to the north, Segovia street - a deep ravine formerly occupied by the San Pedro Stream which empties into the Manzanares River, to the south there is la Ronda and Puerta de Toledo, on the east there is Toledo street - bordering Rastro and the district of Lavapiés - and to the west, Bailen street.

Centro is a district of Madrid, Spain. It is approximately 5.23 km2 in size. It has a population of 149,718 people and a population density of 28,587/km2. It roughly corresponds to the bulk of the housing formerly enclosed by the so-called Walls of Philip IV. The district is made up of the neighbourhoods of Cortes, Embajadores, Justicia, Universidad, Palacio and Sol.