The 1322 Battle of Burton Bridge was fought between Thomas, 2nd Earl of Lancaster and his cousin King Edward II of England during the Despenser War. Edward's army was proceeding northwards to engage Lancaster, having defeated his Marcher Lord allies in Wales. Lancaster fortified the bridge at Burton upon Trent, an important crossing of the River Trent, in an attempt to prevent the King from proceeding. Edward arrived at nearby Cauldwell on 7 March 1322 and intended to use the ford at Walton-on-Trent to cross the river and outflank Lancaster. Edward was delayed for three days by floodwaters, during which time some of his force was deployed opposite Lancaster's men at the bridge.

The Despenser War (1321–22) was a baronial revolt against Edward II of England led by the Marcher Lords Roger Mortimer and Humphrey de Bohun. The rebellion was fuelled by opposition to Hugh Despenser the Younger, the royal favourite. After the rebels' summer campaign of 1321, Edward was able to take advantage of a temporary peace to rally more support and a successful winter campaign in southern Wales, culminating in royal victory at the Battle of Boroughbridge in the north of England in March 1322. Edward's response to victory was his increasingly harsh rule until his fall from power in 1326.