The Battle of Cana was fought between Greek Seleucid Empire under king Antiochus XII Dionysus, and the Arab Nabataean Kingdom. Cana is an unknown village; scholars place it somewhere south or southwest of the Dead Sea.

Antiochus XII Dionysus Epiphanes Philopator Callinicus was a Hellenistic Seleucid monarch who reigned as King of Syria between 87 and 82 BC. The youngest son of Antiochus VIII and, most likely, his Egyptian wife Tryphaena, Antiochus XII lived during a period of civil war between his father and his uncle Antiochus IX, which ended with the assassination of Antiochus VIII in 96 BC. Antiochus XII's four brothers laid claim to the throne, eliminated Antiochus IX as a claimant, and waged war against his heir Antiochus X.