The Battle of Hembrillo Basin was fought April 5–8, 1880 between the United States Army against a combined band of Chiricahua and Mescalero Apaches led by Chief Victorio. Hembrillo Basin was the largest battle of Victorio's War, although casualties were light on both sides. Victorio held off an attack by superior numbers of army soldiers and Indian scouts, evacuated his women and children from the battlefield, and withdrew successfully. Hembrillo Basin is located on the White Sands Missile Range and access by the public is strictly regulated.

Victorio was a warrior and chief of the Warm Springs band of the Tchihendeh division of the central Apaches in what is now the American states of Texas, New Mexico, Arizona, and the Mexican states of Sonora and Chihuahua.