The Battle of Megiddo was fought between Egyptian forces under the command of Pharaoh Thutmose III and a large rebellious coalition of Canaanite vassal states led by the king of Kadesh. It is the first battle to have been recorded in what is accepted as relatively reliable detail. Megiddo is also the first recorded use of the composite bow and the first body count. All details of the battle come from Egyptian sources—primarily the hieroglyphic writings on the Hall of Annals in the Temple of Amun-Re at Karnak, Thebes, by the military scribe Tjaneni.

Thutmose III, sometimes called Thutmose the Great, was the sixth pharaoh of the 18th Dynasty. Officially he ruled Egypt from 28 April 1479 BC until 11 March 1425 BC, commencing with his coronation at the age of two and concluding with his death, aged fifty-six; however, during the first 22 years of his reign, he was coregent with his stepmother and aunt, Hatshepsut, who was named the pharaoh. While he was shown first on surviving monuments, both were assigned the usual royal names and insignia and neither is given any obvious seniority over the other. Thutmose served as the head of Hatshepsut's armies. During the final two years of his reign, he appointed his son and successor, Amenhotep II, as his junior co-regent. His firstborn son and heir to the throne, Amenemhat, predeceased Thutmose III.