The Battle of Nazareth began on 20 September 1918, during the Battle of Sharon, which together with the Battle of Nablus formed the set piece Battle of Megiddo fought during the last months of the Sinai and Palestine Campaign of the First World War. During the cavalry phase of the Battle of Sharon the Desert Mounted Corps rode to the Esdraelon Plain 40 and 50 miles behind the front line in the Judean Hills. At Nazareth on the plain, the 13th Cavalry Brigade of the 5th Cavalry Division attempted to capture the town and the headquarters of the Yildirim Army Group which was eventually captured the following day after the garrison had withdrawn.

The Battle of Sharon fought between 19 and 25 September 1918, began the set piece Battle of Megiddo half a day before the Battle of Nablus, in which large formations engaged and responded to movements by the opposition, according to pre-existing plans, in the last months of the Sinai and Palestine Campaign of World War I. The fighting took place over a wide area from the Mediterranean Sea east to the Rafat salient in the Judean Hills. Here the Egyptian Expeditionary Force (EEF) XXI Corps with the French brigade sized Détachement Français de Palestine et de Syrie attacked the Yildirim Army Group Eighth Army's XXII Corps and German Asia Corps. The Battle of Sharon extended well behind the Ottoman front lines when the Desert Mounted Corps rode through a gap in the front line across the Plain of Sharon to occupy the Esdraelon Plain. Meanwhile, during the Battle of Nablus the XX Corps attacked Nablus while Chaytor's Force held the right flank in the Jordan Valley before advancing to secure bridges and fords across the Jordan River, to continue the encirclement the defenders in the Judean Hills. Subsequently, Chaytor's Force advanced against the Fourth Army to capture Es Salt and Amman after the Second Battle of Amman.