The Battle of Samakh was fought on 25 September 1918, during the Battle of Sharon which together with the Battle of Nablus formed the set piece Battle of Megiddo fought from 19 to 25 September 1918, in the last months of the Sinai and Palestine Campaign of the First World War. During the cavalry phase of the Battle of Sharon the Desert Mounted Corps commanded by the Australian Lieutenant General Harry Chauvel, captured the Esdraelon Plain 40–50 miles (64–80 km) behind the front line in the Judean Hills on 20 September, when the 3rd Light Horse Brigade captured Jenin. The 4th Light Horse Brigade, Australian Mounted Division was deployed guarding supply columns, and prisoners, before being ordered to attack and capture Samakh on the shore of the Sea of Gallilee. Here the Ottoman and German garrison had been ordered by the commander of the Yildirim Army Group to fight to the last man.

The Battle of Sharon fought between 19 and 25 September 1918, began the set piece Battle of Megiddo half a day before the Battle of Nablus, in which large formations engaged and responded to movements by the opposition, according to pre-existing plans, in the last months of the Sinai and Palestine Campaign of World War I. The fighting took place over a wide area from the Mediterranean Sea east to the Rafat salient in the Judean Hills. Here the Egyptian Expeditionary Force (EEF) XXI Corps with the French brigade sized Détachement Français de Palestine et de Syrie attacked the Yildirim Army Group Eighth Army's XXII Corps and German Asia Corps. The Battle of Sharon extended well behind the Ottoman front lines when the Desert Mounted Corps rode through a gap in the front line across the Plain of Sharon to occupy the Esdraelon Plain. Meanwhile, during the Battle of Nablus the XX Corps attacked Nablus while Chaytor's Force held the right flank in the Jordan Valley before advancing to secure bridges and fords across the Jordan River, to continue the encirclement the defenders in the Judean Hills. Subsequently, Chaytor's Force advanced against the Fourth Army to capture Es Salt and Amman after the Second Battle of Amman.