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Beatrice Mintz
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Beatrice Mintz was an American embryologist who contributed to the understanding of genetic modification, cellular differentiation, and cancer, particularly melanoma. Mintz was a pioneer of genetic en
Biologist Beatrice Mintz
Biologist Beatrice Mintz
A chimeric mouse (right) and her pups, demonstrating how cells from different donor strains result in a mosaic coat color in the chimera; note her one
A chimeric mouse (right) and her pups, demonstrating how cells from different donor strains result in a mosaic coat color in the chimera; note her one pink eye
Ralph L. Brinster
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Ralph Lawrence Brinster is an American geneticist, National Medal of Science laureate, and Richard King Mellon Professor of Reproductive Physiology at the School of Veterinary Medicine, University of
Beatrice Mintz
…first scientists to generate both chimeric and transgenic mammals. In 1996, she shared the inaugural March of Dimes Prize in Developmental Biology with Ralph L. Brinster for their work in developing transgenic mice. Much of her career was spent at Fox Chase Cancer Center in Philadelphia where, in 2002, she was appointed…
Brinster in October 2011
Brinster in October 2011
Fig. 2. Chimeric mouse. This mouse resulted from a blastocyst, which normally would produce a white mouse, that was injected with teratocarcinoma cell
Fig. 2. Chimeric mouse. This mouse resulted from a blastocyst, which normally would produce a white mouse, that was injected with teratocarcinoma cells from a brown mouse. The dark stripes on the mouse represent the contribution of the foreign brown-type cells.
Fig. 5. Top panel. Recipient mouse testis that was injected with genetically modified spermatogonial stem cells containing a reporter transgene for Gr
Fig. 5. Top panel. Recipient mouse testis that was injected with genetically modified spermatogonial stem cells containing a reporter transgene for Green Fluorescent Protein (GFP), which will fluoresce green. Bottom Panel. The testis will produce spermatozoa that transmitted the GFP transgene to offspring.
Professor Ralph Brinster receiving the National Medal of Science from President Barack Obama.
Professor Ralph Brinster receiving the National Medal of Science from President Barack Obama.