Belfast Harlequins is a multi-sports club located off the Malone Road in south Belfast, Northern Ireland. The club name provides the overall umbrella for rugby union, men's and ladies' hockey, and squash. The club is associated on and off the field with Methodist College Belfast (MCB).

The Malone Road is a radial road in Belfast, Northern Ireland, leading from the university quarter southwards to the affluent suburbs of Malone and Upper Malone, each a separate electoral ward. The road runs parallel to the Lisburn Road and is linked by over a dozen side streets, while at its northern end, the Stranmillis Road rejoins the Malone Road to form University Road, which in turn joins with the Lisburn Road to become Bradbury Place. Most of the road is in the BT9 postcode district.