Bernice is a town in Union Parish, Louisiana, United States. The population was 1,689 at the 2010 census, a decrease from 1,809 in 2000. It is part of the Monroe Metropolitan Statistical Area.

Union Parish is a parish located in the north central section of the U.S. state of Louisiana. As of the 2020 census, the population was 21,107. The parish seat is Farmerville. The parish was created on March 13, 1839, from a section of Ouachita Parish. Its boundaries have changed four times since then.