Berwickshire or the County of Berwick is a historic county, registration county and lieutenancy area in south-eastern Scotland, on the English border. The county takes its name from Berwick-upon-Tweed, its original county town, which was part of Scotland at the time of the county's formation in the twelfth century, but became part of England in 1482 after several centuries of swapping back and forth between the two kingdoms. After the loss of Berwick, Duns and Greenlaw both served as county town at different periods.

The shires of Scotland, or counties of Scotland, are historic subdivisions of Scotland established in the Middle Ages and used as administrative divisions until 1975. Originally established for judicial purposes, from the 17th century they started to be used for local administration purposes as well. The areas used for judicial functions (sheriffdoms) came to diverge from the shires, which ceased to be used for local government purposes after 1975 under the Local Government (Scotland) Act 1973.