Big Brother and the Holding Company is an American rock band that formed in San Francisco in 1965 as part of the same psychedelic music scene that produced the Grateful Dead, Quicksilver Messenger Service, and Jefferson Airplane. After some initial personnel changes, the band became well known with the lineup of vocalist Janis Joplin, guitarists Sam Andrew and James Gurley, bassist Peter Albin, and drummer Dave Getz. Their second album Cheap Thrills, released in 1968, is considered one of the masterpieces of the psychedelic sound of San Francisco; it reached number one on the Billboard charts, and was ranked number 338 in Rolling Stone's the 500 greatest albums of all time. The album is also listed in the book 1001 Albums You Must Hear Before You Die.

The San Francisco sound refers to rock music performed live and recorded by San Francisco-based rock groups of the mid-1960s to early 1970s. It was associated with the counterculture community in San Francisco, particularly the Haight-Ashbury district, during these years. San Francisco is a westward-looking port city, a city that at the time was 'big enough' but not manic like New York City or spread out like Los Angeles. Hence, it could support a 'scene'. According to journalist Ed Vulliamy, "A core of Haight Ashbury bands played with each other, for each other"