Big Spring is a city in and the county seat of Howard County, Texas, United States, at the crossroads of U.S. Highway 87 and Interstate 20. With a population of 27,282 as of the 2010 census, it is the largest city between Midland to the west, Abilene to the east, Lubbock to the north, and San Angelo to the south. Big Spring was established as the county seat of Howard County in 1882; it is the largest community in the county.

Howard County is a county located in the U.S. state of Texas. At the 2020 census, its population was 34,860. Its county seat is Big Spring. The county was created in 1876 and organized in 1882. It is named for Volney E. Howard, a U.S. Congressman from Texas.