Biggs Junction is an unincorporated community in Sherman County, Oregon, United States. For statistical purposes, the United States Census Bureau has defined Biggs Junction as a census-designated place (CDP). The census definition of the area may not precisely correspond to local understanding of the area with the same name.

Sherman County is one of the 36 counties in the U.S. state of Oregon. As of the 2020 census, the population was 1,870, making it the second-least populous county in Oregon after nearby Wheeler. The county seat is Moro, and the largest city is Wasco. The county is named for William Tecumseh Sherman, a Union general in the American Civil War.