Billy Boy & Mary Lou is a studio album by American country music artists Bill Anderson and Mary Lou Turner. It was released in June 1977 on MCA Records and was produced by Buddy Killen. It was the duo's second studio album together since pairing up as a duet team in the mid 1970s. The album produced two singles between 1977 and 1978. It would be the duo's final studio album together.

James William Anderson III, known professionally as Bill Anderson, is an American country music singer, songwriter, and television host. His soft-spoken singing voice was given the nickname "Whispering Bill" by music critics and writers. As a songwriter, his compositions have been covered by various music artists since the late 1950s, including Ray Price and George Strait.