William Edward Crystal is an American comedian, actor, and filmmaker. Crystal is known as a standup comedian and for his film and stage roles. Crystal has received numerous accolades, including six Primetime Emmy Awards and a Tony Award as well as nominations for three Grammy Awards and three Golden Globe Awards. He was honored with a star on the Hollywood Walk of Fame in 1991, the Mark Twain Prize for American Humor in 2007, the Critics' Choice Lifetime Achievement Award in 2022, and the Kennedy Center Honors in 2023.

The Mark Twain Prize for American Humor is an American award presented by the John F. Kennedy Center for the Performing Arts in Washington, D.C. annually since 1998, except for the years 2020 and 2021. Named after the 19th-century humorist Mark Twain, it is presented to individuals who have "had an impact on American society in ways similar to" Twain. The Kennedy Center chose Twain in recognition of his role as a controversial social commentator and his "uncompromising perspective of social injustice and personal folly." A copy of Karl Gerhardt's 1884 bust of Twain is presented in an autumn ceremony at the Kennedy Center Concert Hall, during which the honoree is celebrated by his or her peers. The event is a significant fundraiser to benefit the Kennedy Center, which sells tickets as well as access to dinners and after-parties featuring the celebrities.