Bion-M No.1 (Бион-М) was a Russian space mission, part of the Bion-M programme focused on space medicine. The new generation Bion-M continued the Soviet/Russian Bion satellite programme aimed at biological research in space. The last spacecraft of the Bion series, Bion 11, was launched in 1996. The Bion-M1 spacecraft was designed to carry biological, physiological and biotechnological experiments to low Earth orbit and return them to Earth at the end of the mission. The biological payload for Bion-M1 included rodents, amphibians, reptiles, crustaceans, mollusks, fish, insects, bacteria, plant and animal cell cultures. The spacecraft was the result of collaboration hosting biomedical payloads provided by scientific institutions from the United States, Germany, Canada, the Netherlands, Poland and other countries. The Bion-M automated spacecraft was a unique specialized space complex that aimed to determine the fundamental mechanisms of how life adapts to microgravity and then readapts to Earth-normal gravity.

The Bion satellites, also named Biocosmos, is a series of Soviet biosatellites focused on space medicine.