The Birmingham and Gloucester Railway (B&GR) was the first name of the railway linking the cities in its name and of the company which pioneered and developed it; the line opened in stages in 1840, using a terminus at Camp Hill in Birmingham. It linked with the Bristol and Gloucester Railway in Gloucester, but at first that company's line was broad gauge, and Gloucester was a point of the necessary but inconvenient transhipment of goods and passengers onto 4 ft 8+1⁄2 in gauge that became the national standard. Nearly all of the original main line remains active as a "trunk" route, also known as an arterial route or line.

The River Avon in central England flows generally southwestwards and is a major left-bank and easternmost tributary of the River Severn. It is also known as the Warwickshire Avon or Shakespeare's Avon, to distinguish it from several other rivers of the same name in the United Kingdom.