Bryon Anthony McCane II, better known by his stage name Bizzy Bone, is an American rapper, singer and the youngest member of the Cleveland rap group Bone Thugs-n-Harmony.

Bone Thugs-n-Harmony is an American hip hop group composed of rappers Bizzy Bone, Wish Bone, Layzie Bone, Krayzie Bone, and Flesh-n-Bone. Formed in 1991 in Cleveland, Ohio, the group signed to fellow American rapper Eazy-E's Ruthless Records in late 1993, on which they debuted with their EP Creepin on ah Come Up the next year. The EP included their breakout hit single "Thuggish Ruggish Bone". In 1995, the group released its second album E. 1999 Eternal, which included hits "1st of tha Month" and "East 1999". Their hit song "Tha Crossroads", a tribute to then-recently deceased mentor Eazy-E, won a Grammy Award in 1997.