Blackfriars Bridge is a stone arch bridge in Greater Manchester, England. Completed in 1820, it crosses the River Irwell, connecting Salford to Manchester.

The River Irwell is a tributary of the River Mersey in north-west England. It rises at Irwell Springs on Deerplay Moor, approximately 1+1⁄2 miles north of Bacup and flows southwards for 39 mi (63 km) to meet the Mersey near Irlam. The Irwell marks the boundary between Manchester and Salford, and its lower reaches have been canalised and now form part of the Manchester Ship Canal.