The Blackstone Valley or Blackstone River Valley is a region of Massachusetts and Rhode Island. It was a major factor in the American Industrial Revolution. It makes up part of the Blackstone River Valley National Heritage Corridor and National Historical Park.

Northbridge is a town in Worcester County, Massachusetts, United States. The population was 16,335 at the 2020 census. The Northbridge Town Hall is located at 7 Main Street in Whitinsville. The town is now a part of the Blackstone River Valley National Heritage Corridor, of the National Park Service. Northbridge claims to history include: Native American Nipmuc lands, Colonel John Spring, who led the Uxbridge militia training company in the American Revolution, Samuel Spring, Revolutionary War Chaplain, the Residence of Ezra T. Benson 1830–1832, the birthplace of President Millard Fillmore's mother, Phoebe, and home to the Whitin Machine Works from 1831 to 1964.