Blossom is an American sitcom that aired for five seasons on NBC. Debuting as a pilot preview on July 5, 1990, it premiered as a mid-season replacement on January 3, 1991, and aired until May 22, 1995. Don Reo created the series, which starred Mayim Bialik as Blossom Russo, a teenager who lived with her father and two elder brothers. It was produced by Reo's Impact Zone Productions and Witt/Thomas Productions in association with Touchstone Television.

Mayim Chaya Bialik is an American actress, author and former game show host. From 1991 to 1995, she played the title character of the NBC sitcom Blossom. From 2010 to 2019, she played neuroscientist Amy Farrah Fowler on the CBS sitcom The Big Bang Theory, for which she was nominated four times for the Primetime Emmy Award for Outstanding Supporting Actress in a Comedy Series and won the Critics' Choice Television Award for Best Supporting Actress in a Comedy Series in 2015 and 2017. Bialik shared hosting duties of Jeopardy! with Ken Jennings on a rotating basis between August 2021 and December 2023.