The Bohr effect is a phenomenon first described in 1904 by the Danish physiologist Christian Bohr. Hemoglobin's oxygen binding affinity (see oxygen–haemoglobin dissociation curve) is inversely related both to acidity and to the concentration of carbon dioxide. That is, the Bohr effect refers to the shift in the oxygen dissociation curve caused by changes in the concentration of carbon dioxide or the pH of the environment. Since carbon dioxide reacts with water to form carbonic acid, an increase in CO2 results in a decrease in blood pH, resulting in hemoglobin proteins releasing their load of oxygen. Conversely, a decrease in carbon dioxide provokes an increase in pH, which results in hemoglobin picking up more oxygen.
Christian Bohr, who was credited with the discovery of the effect in 1904.
Though they are one of the largest animals on the planet, humpback whales have a Bohr effect magnitude similar to that of a guinea pig.
Christian Harald Lauritz Peter Emil Bohr (1855–1911) was a Danish physician, father of the physicist and Nobel laureate Niels Bohr, as well as the mathematician and football player Harald Bohr and grandfather of another physicist and Nobel laureate Aage Bohr. He married Ellen Adler in 1881.
Christian Bohr
