Boone County is a county in the U.S. state of West Virginia. As of the 2020 census, the population was 21,809. Its county seat is Madison. Boone County is part of the Charleston, WV Metropolitan Statistical Area. Leading industries and chief agricultural products in Boone County include coal, lumber, natural gas, tobacco, and strawberries.

Madison is a city and former coal town in Boone County, West Virginia, United States. The population was 2,911 at the 2020 census. It is the county seat of Boone County.