The Boston Post Road was a system of mail-delivery routes between New York City and Boston, Massachusetts, that evolved into one of the first major highways in the United States.

A post road is a road designated for the transportation of postal mail. In past centuries, only major towns had a post house and the roads used by post riders or mail coaches to carry mail among them were particularly important ones or, due to the special attention given them, became so. In various centuries and countries, post road became more or less equivalent to main road, royal road, or highway. The 20th century spread of postal service blurred the distinction.