Brachypelma hamorii is a vulnerable species of tarantula found in Mexico. It has been confused with B. smithi; both have been called Mexican redknee tarantulas. Many earlier sources referring to B. smithi either do not distinguish between the two species or relate to B. hamorii. B. hamorii is a terrestrial tarantula native to the western faces of the Sierra Madre Occidental and Sierra Madre del Sur mountain ranges in the Mexican states of Colima, Jalisco, and Michoacán. The species is a large spider, adult females having a total body length over 50 mm (2 in) and males having legs up to 75 mm (3 in) long. Mexican redknee tarantulas are a popular choice for enthusiasts. Like most tarantulas, it has a long lifespan.

A vulnerable species is a species which has been categorized by the International Union for Conservation of Nature as being threatened with extinction unless the circumstances that are threatening its survival and reproduction improve.