Branham High School is a secondary school in San Jose, California, located in the Cambrian neighborhood within the West San Jose region. It originally opened on September 13, 1967, under the Campbell Union High School District (CUHSD) before closing in 1991. The District leased the campus to Valley Christian Schools in 1991. The school was reopened by CUHSD in 1999 due to increased enrollment within the district. It is named after Isaac Branham, a Californian pioneer who became a successful farmer and lumber mill owner.

Cambrian is a neighborhood of San Jose, California, located in South San Jose. Though most of the neighborhood is incorporated as part of San Jose, a small portion exists as an unincorporated census-designated place called Cambrian Park.