Brazil nut refers to a South American tree of the monotypic genus Bertholletia in the family Lecythidaceae as well as the tree's commercially-harvested edible seeds. It is one of the largest and longe
Bertholletia excelsa compose
Brazil nut fruit attached to branch
Freshly cut Brazil nut fruit
Selenium is an essential mineral micronutrient for animals, though it is toxic in large doses. In plants, it sometimes occurs in toxic amounts as forage, e.g. locoweed. Selenium is a component of the
Brazil nut
…manganese, potassium, and zinc. Calcium and iron are present in moderate amounts (10–19% DV; table). Brazil nuts are a particularly rich source of selenium, with just 28 g (0.99 oz) – a standard serving of around 6 to 8 nuts, depending on size – has an average of 544 micrograms of selenium or 10 times the…
Relationship between survival of juvenile salmon and concentration of selenium in their tissues after 90 days (Chinook salmon) or 45 days (Atlantic salmon) exposure to dietary selenium. The 10% lethality level (LC10=1.84 μg/g) was derived by applying the biphasic model of Brain and Cousens to only the Chinook salmon data. The Chinook salmon data comprise two series of dietary treatments, combined here because the effects on survival are indistinguishable.
Selenium at nutritional levels is required for cell homeostasis, playing a role as an anti-oxidant through selenoproteins, thus, act chemo-preventive against cancer. In contrast, supra-nutritional levels act as pro-oxidant toxic in tumour cells.
Selenium can either play a pro-oxidant role inducing ROS, activating the Akt–NF–кB pathway or play an antioxidant role through selenoprotein synthesis such as TXNRD relocating to the nucleus and activating NF-кB, resulting in further activation of leukocytes and pro-inflammatory cytokine genes.