Brindisi railway station is the main station serving the city and comune of Brindisi, in the region of Apulia, southern Italy. Opened in 1865, it forms part of the Adriatic Railway (Ancona–Lecce), and is also a junction for, and terminus of, the Taranto–Brindisi railway.

Lecce railway station serves the city and comune of Lecce, in the region of Apulia, Southern Italy. Opened in 1866, it is the southern terminus of the Adriatic Railway (Ancona–Lecce), and is also the terminus of two regional lines, the Martina Franca–Lecce railway and the Lecce–Otranto railway.