Brookgreen Gardens is a sculpture garden and wildlife preserve, located just south of Murrells Inlet, in the U.S. state of South Carolina. The 9,100-acre (37 km2) property includes several themed gardens featuring American figurative sculptures, the Lowcountry Zoo, and trails through several ecosystems in nature reserves on the property. It was founded by Archer Milton Huntington, stepson of railroad magnate Collis Potter Huntington, and Anna Hyatt Huntington, his wife, to feature sculptures by Anna and her sister Harriet Randolph Hyatt Mayor, along with other American sculptors. Brookgreen Gardens was opened in 1932. It was developed on property of four former rice plantations, taking its name from the former Brookgreen Plantation, which dates to the antebellum period.

Murrells Inlet is an unincorporated area and census-designated place in Georgetown County, South Carolina, United States. The population was 7,547 at the 2010 census. It is about 13 miles south of Myrtle Beach, South Carolina and 21 miles north of Georgetown, the county seat.