Brothers to the Rescue is a Miami-based activist nonprofit organization headed by José Basulto. Formed by Cuban exiles, the group is widely known for its opposition to the Cuban government and its former leader Fidel Castro. The group describes itself as a humanitarian organization aiming to assist and rescue raft refugees emigrating from Cuba and to "support the efforts of the Cuban people to free themselves from dictatorship through the use of active non-violence". Brothers to the Rescue, Inc., was founded in May 1991 "after several pilots were touched by the death of" fifteen-year-old Gregorio Perez Ricardo, who "fleeing Castro's Cuba on a raft, perished of severe dehydration in the hands of U.S. Coast Guard officers who were attempting to save his life."

The Cuban Five, also known as the Miami Five, are five Cuban intelligence officers who were arrested in September 1998 and later convicted in Miami of conspiracy to commit espionage, conspiracy to commit murder, acting as an agent of a foreign government, and other illegal activities in the United States. The Five were in the United States to observe and infiltrate the Cuban-American groups Alpha 66, the F4 Commandos, the Cuban American National Foundation, and Brothers to the Rescue. They were part of La Red Avispa composed of at least 27 Cuban spies.