Brownsville is a borough in Fayette County, Pennsylvania, United States, first settled in 1785 as the site of a trading post a few years after the defeat of the Iroquois enabled a resumption of westward migration after the Revolutionary War. The trading post soon became a tavern and inn and was receiving emigrants heading west, as it was located above the cut bank overlooking the first ford that could be reached to those descending from the Allegheny Mountains. Brownsville is located 40 miles (64 km) south of Pittsburgh along the east bank of the Monongahela River.

Fayette County is a county in the Commonwealth of Pennsylvania. It is located in southwestern Pennsylvania, adjacent to Maryland and West Virginia. As of the 2020 census, the population was 128,804. Its county seat is Uniontown. The county was created on September 26, 1783, from part of Westmoreland County and named after the Marquis de Lafayette. The county is part of the Southwest Pennsylvania region of the state.