Bryophyllum is a group of plant species of the family Crassulaceae native to Madagascar. It is a section or subgenus within the genus Kalanchoe, and was formerly placed at the level of genus. This section is notable for vegetatively growing small plantlets on the fringes of the leaves; these eventually drop off and root. These plantlets arise from mitosis of meristematic-type tissue in notches in the leaves.

The Crassulaceae, also known as the stonecrop family or the orpine family, are a diverse family of dicotyledon flowering plants characterized by succulent leaves and a unique form of photosynthesis, known as Crassulacean acid metabolism (CAM). Flowers generally have five floral parts. Crassulaceae are usually herbaceous but there are some subshrubs, and relatively few treelike or aquatic plants. Crassulaceae are a medium-sized monophyletic family in the core eudicots, among the order Saxifragales, whose diversity has made infrafamilial classification very difficult. The family includes approximately 1,400 species and 34–35 genera, depending on the circumscription of the genus Sedum, and distributed over three subfamilies. Members of the Crassulaceae are found worldwide, but mostly in the Northern Hemisphere and southern Africa, typically in dry and/or cold areas where water may be scarce, although a few are aquatic.