Bukhara Region is a region of Uzbekistan located in the southwest of the country. The Kyzyl Kum desert takes up a large portion of its territory. It borders Turkmenistan, Navoiy Region, Qashqadaryo Region, a small part of the Xorazm Region, and the Karakalpakstan Republic. It covers an area of 40,216 km2. The population is estimated at 1,976,823 (2022), with 63% living in rural areas.

Navoiy Region is one of the regions of Uzbekistan. It is located in the central north/northwest of the country. It covers an area of 111,095 km2 (42,894 sq mi), which makes it the largest of the regions of Uzbekistan. The Navoiy region borders with Kazakhstan, Samarqand Region, Buxoro Region, Jizzakh Region, and the Karakalpakstan Republic. The population is estimated 1,033,857 (2022), with 51% living in rural areas. The capital is Navoiy. The region and its capital are named after the poet Ali-Shir Nava'i.