Byesville is a village in Guernsey County, Ohio, United States, along Wills Creek. The population was 2,364 at the 2020 census.

Guernsey County is a county located in the U.S. state of Ohio. As of the 2020 census, the population was 38,438. Its county seat and largest city is Cambridge. It is named for the Isle of Guernsey in the English Channel, from which many of the county's early settlers emigrated.