C.C. DeVille is an American guitarist who is a member of rock band Poison. The band has sold more than 50 million albums worldwide, including 15 million in the United States. In 1998 he formed a band called Samantha 7.

Poison is an American glam metal band formed in 1983 in Mechanicsburg, Pennsylvania. The most successful incarnation of the band consists of lead singer and rhythm guitarist Bret Michaels, drummer Rikki Rockett, lead guitarist and backing vocalist C.C. DeVille, and bassist Bobby Dall. The band achieved huge commercial success in the mid-1980s through the mid-1990s and has sold 30 million records in the United States and over 65 million albums worldwide.