Ca' Rezzonico is a palazzo and art museum on the Grand Canal in the Dorsoduro sestiere of Venice, Italy. It is a particularly notable example of the 18th century Venetian baroque and rococo architecture and interior decoration, and displays paintings by the leading Venetian painters of the period, including Francesco Guardi and Giambattista Tiepolo. It is a public museum dedicated to 18th-century Venice and one of the 11 venues managed by the Fondazione Musei Civici di Venezia.

The Grand Canal is a channel in Venice, Italy. It forms one of the major water-traffic corridors in the city.