The Cadillac V-16 was Cadillac's top-of-the-line model from its January 1930 launch until 1940. The V16 powered car was a first in the United States, both extremely expensive and exclusive, with every chassis being custom-finished to order. Only 4,076 were constructed in its 11-year run, with the majority built in its debut year before the Great Depression took strong hold. The onset of World War II reduced the sales, resulting in its demise. It was, however, at least three times cheaper than Bugatti Royale.

Cadillac Motor Car Division, or simply Cadillac, is a division of the American automobile manufacturer General Motors (GM) that designs and builds luxury vehicles. Its major markets are the United States, Canada and China. Cadillac models are distributed in 34 additional markets worldwide. Historically, Cadillac automobiles were at the top of the luxury field within the United States, but have been outsold by European luxury brands including BMW and Mercedes since the 2000s. In 2019, Cadillac sold 390,458 vehicles worldwide, a record for the brand.