The caduceus is the staff carried by Hermes in Greek mythology and consequently by Hermes Trismegistus in Greco-Egyptian mythology. The same staff was borne by other heralds like Iris, the messenger of Hera. The short staff is entwined by two serpents, sometimes surmounted by wings. In Roman iconography, it was depicted being carried in the left hand of Mercury, the messenger of the gods.
Fresco from Pompeii of the punishment of Ixion: in the center is Mercury holding the caduceus
Iris with the caduceus in detail from an Attic red-figure pelike, middle of fifth century BC (Agrigento, Sicily)
Coin from Sardis (Turkey) with caduceus (c. 140-144 CE)
Ningishzida was a Mesopotamian deity of vegetation, the underworld and sometimes war. He was commonly associated with snakes. Like Dumuzi, he was believed to spend a part of the year in the land of the dead. He also shared many of his functions with his father Ninazu.
Ningishzida on the libation vase of Gudea, circa 2100 BCE
The "libation vase of Gudea" with the dragon Mušḫuššu, dedicated to Ningishzida, circa 2100 BCE (short chronology). The caduceus-like symbol (right) is interpreted as a representation of the god himself. Inscription: "To the god Ningiszida, his god, Gudea, Ensi (governor) of Lagash, for the prolongation of his life, has dedicated this"
The name Ningishzida inscribed on a statue of Ur-Ningirsu.