Caffe Cino was an Off-Off-Broadway theater founded in 1958 by Joe Cino. The West Village coffeehouse, located at 31 Cornelia Street, was initially conceived as a venue for poetry, folk music, and visual art exhibitions. The plays produced at the Cino, however, became most prominent, and it is now considered the "birthplace of Off-Off-Broadway".

Off-off-Broadway theaters are smaller New York City theaters than Broadway and off-Broadway theaters, and usually have fewer than 100 seats. The off-off-Broadway movement began in 1958 as part of a response to perceived commercialism of the professional theatre scene and as an experimental or avant-garde movement of drama and theatre. Over time, some off-off-Broadway productions have moved away from the movement's early experimental spirit.