Caguana is a barrio in the municipality of Utuado, Puerto Rico. Its population in 2010 was 4,009.

Utuado is a town and municipality of Puerto Rico located in the central mountainous region of the island known as the Cordillera Central. It is located north of Adjuntas and Ponce; south of Hatillo and Arecibo; east of Lares; and west of Ciales and Jayuya. It is the third-largest municipality in land area in Puerto Rico. According to the 2020 US Census, the municipality has a population of 28,287 spread over 24 barrios and Utuado pueblo.